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KMID : 0370219950390010031
Yakhak Hoeji
1995 Volume.39 No. 1 p.31 ~ p.35
Efficient Synthesis of 10-Membered Lactone Possessing Ring-olefin at 7,8-Position



Abstract
An unusual 10-membered lactone possesing ring-olefin at 7,8-position has been efficiently synthesized. The w-hydroxy acid as a cyclization precusor was derived from c-caprolactone in 41% overall yield of 7 steps and efficiently cyclized by Mukaiyama procedure.
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